abstract：:This study investigated whether pretreatment with glycopyrronium can attenuate the hypotension caused by anaesthesia of the elderly with propofol. Twenty elderly patients (77.1 +/- 2.44 years, mean +/- SEM) of ASA physical status 2 or 3 scheduled for elective urological procedures were given glycopyrronium 0 (n = 10) ...

journal_title：Anaesthesia

authors： Sneyd JR,Mayall R

更新日期：1992-07-01 00:00:00

abstract：:The possibility exists that agents used in anaesthesia may have adverse teratogenic effects on staff, patients, and developing fetuses. It has been shown that a range of neurotropic drugs, when injected into pregnant mice on the 9th day of gestation, produce a characteristic group of central nervous system malformatio...

journal_title：Anaesthesia

authors： Martin LV,Jurand A

更新日期：1992-06-01 00:00:00

abstract：:A double-blind controlled study was performed to assess the efficacy and safety of patient-controlled analgesia in burn patients. This method was compared with conventional analgesic therapy consisting of intermittent intravenous morphine injections. Twenty-four adult patients hospitalised for burn injuries participat...

journal_title：Anaesthesia

authors： Choiniere M,Grenier R,Paquette C

更新日期：1992-06-01 00:00:00

abstract：:The large lateral hole of the Sprotte needle is claimed to aid cerebrospinal fluid efflux during the performance of spinal anaesthesia. Using theoretical calculations and practical measurement we have shown that reducing the area of the lateral hole to that of the cross sectional area of the needle does not affect the...

journal_title：Anaesthesia

authors： Aglan MY,Stansby PK

更新日期：1992-06-01 00:00:00

abstract：:The effects of propofol during low flow (1.6 l.min-1.m-2) hypothermic (27-29 degrees C) cardiopulmonary bypass on systemic haemodynamic and metabolic variables were studied in 20 patients in a parallel group comparison. Patients in the control group underwent two consecutive control periods, whereas those in the propo...

journal_title：Anaesthesia

authors： Laycock GJ,Alston RP

更新日期：1992-05-01 00:00:00

abstract：:Twenty-six patients received oral temazepam and subsequently spinal anaesthesia. Blood and lumbar cerebrospinal fluid temazepam levels were measured together with the degree of sedation. The plasma and cerebrospinal fluid concentrations correlated well with the temazepam dose but even better with the weight standardis...

journal_title：Anaesthesia

authors： Osborne GA,Badcock NR,McGrath PM,Russell WJ,Frewin DB

更新日期：1992-04-01 00:00:00

abstract：:Laryngeal mask airways and tracheal tubes were studied to determine both their resistance to constant gas flows and additional inspiratory work during simulated inspiration. Laryngeal mask airways imposed less resistance and required lower additional inspiratory work compared with the corresponding sized tracheal tube...

journal_title：Anaesthesia

authors： Bhatt SB,Kendall AP,Lin ES,Oh TE

更新日期：1992-04-01 00:00:00

abstract：:A patient with severe Guillain-Barré syndrome responded to treatment with high-dose intravenous immunoglobulins. It is suggested, on the basis of recent case reports, that immunoglobulins may have an important rôle in the future treatment of this immune-mediated disease. ...

journal_title：Anaesthesia

authors： Rajah A

更新日期：1992-03-01 00:00:00

abstract：:We report a rare complication following transfusion of a large volume of blood in an adult patient. An electrophysiological disturbance of the cardiac cycle with prolongation of the QT interval developed, which was followed by recurrent episodes of torsade de pointes, a unique form of ventricular tachycardia. The most...

journal_title：Anaesthesia

authors： Kulkarni P,Bhattacharya S,Petros AJ

更新日期：1992-02-01 00:00:00

abstract：:We have compared the performance of the Baxter disposable with the Graseby electronic patient-controlled analgesia system in 30 patients following major gynaecological surgery. Patients were allocated randomly to receive analgesia via the Baxter or Graseby device for postoperative pain relief. There were no significan...

journal_title：Anaesthesia

authors： Robinson SL,Rowbotham DJ,Mushambi M

更新日期：1992-02-01 00:00:00

abstract：:A 5-year-old girl with Noonan's syndrome and a hypertrophic cardiomyopathy presented for myelography and subsequently, laminectomy. The anaesthetic management of the patient is described and the potential problems of the facial, cardiovascular and skeletal abnormalities associated with the condition are discussed. ...

journal_title：Anaesthesia

authors： Campbell AM,Bousfield JD

更新日期：1992-02-01 00:00:00

abstract：:An internal jugular catheter, which was inserted into a patient with a traumatic haemopneumothorax, accidentally entered the pleural cavity. This was initially undetected because the two signs most frequently used to confirm correct placement, those of blood reflux and fluctuation of central venous pressure with respi...

journal_title：Anaesthesia

authors： Pina J,Morujão N,Castro-Tavares J

更新日期：1992-01-01 00:00:00

abstract：:The aim of this study was to examine the effect of propofol and propofol with suxamethonium on serum potassium concentration during induction of general anaesthesia. Forty patients were studied during elective surgery and serum electrolytes were measured before and after the induction of anaesthesia. Patients were all...

journal_title：Anaesthesia

authors： Fogarty DJ,McCleane GJ

更新日期：1992-01-01 00:00:00

abstract：:A previously unreported complication of minitracheotomy is described. The minitracheotomy introducer was lost into the pleural cavity and a thoracotomy was required to remove it. ...

journal_title：Anaesthesia

authors： McEwan AI,Francis GA,Clarke JT

更新日期：1991-12-01 00:00:00

abstract：:Dextran is used clinically for plasma volume expansion, improvement of blood flow and thromboprophylaxis, but has been associated with untoward side effects. Immunoprophylaxis with dextran I (hapten), before the infusion of dextran-70, has reduced the incidence of serious dextran-induced anaphylactoid reactions. We re...

journal_title：Anaesthesia

authors： Berg EM,Fasting S,Sellevold OF

更新日期：1991-12-01 00:00:00

abstract：:Intra-ocular pressure was measured before and throughout airway establishment with either the laryngeal mask airway or tracheal tube. Similar measurements were made on removal of either airway and the amount of coughing noted in the first minute after removal. There was a significantly smaller increase in intra-ocular...

journal_title：Anaesthesia

authors： Holden R,Morsman CD,Butler J,Clark GS,Hughes DS,Bacon PJ

更新日期：1991-11-01 00:00:00

abstract：:The extent of airborne environmental bacterial contamination which occurs following tracheal suction has been investigated in patients undergoing intermittent positive pressure ventilation in the intensive therapy unit. Two methods of performing suction, one using a conventional open technique and one using a closed s...

journal_title：Anaesthesia

authors： Cobley M,Atkins M,Jones PL

更新日期：1991-11-01 00:00:00

abstract：:The effects of sufentanil on intracranial pressure, mean arterial pressure, cerebral perfusion pressure and heart rate were studied in 20 neurosurgical intensive care unit patients. Epidural intracranial pressure probes were implanted in patients who suffered head injury, intracerebral haemorrhage or underwent tumour ...

journal_title：Anaesthesia

authors： Weinstabl C,Mayer N,Richling B,Czech T,Spiss CK

更新日期：1991-10-01 00:00:00

abstract：:A 74-year-old man presenting for aortic reconstructive surgery showed severe, previously undiagnosed obstructive sleep apnoea during overnight oximetry monitoring before operation. Postoperatively, in the first 4 hours following extubation, he suffered 238 episodes of respiratory obstruction. These events were associa...

journal_title：Anaesthesia

authors： Reeder MK,Goldman MD,Loh L,Muir AD,Casey KR,Gitlin DA

更新日期：1991-10-01 00:00:00

abstract：:Pressure recordings were made during passage of a Tuohy needle from the interspinous ligament to the subarachnoid space for lumbar drain insertion. Epidural space pressures were always positive. Negative pressures were seen only at the moment of entry into the subarachnoid space. These were artefactual and were caused...

journal_title：Anaesthesia

authors： Telford RJ,Hollway TE

更新日期：1991-09-01 00:00:00

abstract：:We modified a Penlon Nuffield 200 for use in a monoplace hyperbaric oxygen chamber by feeding back the chamber pressure to the reducing valve of the Nuffield 200. This provides a compensating mechanism, allowing the ventilator to deliver adequate tidal volumes at pressures of up to 3 atmospheres. We report the laborat...

journal_title：Anaesthesia

authors： Lewis RP,Szafranski J,Bradford RH,Smith HS,Crabbe GG

更新日期：1991-09-01 00:00:00

abstract：:Four cases of severely mentally handicapped young adults requiring day care dental treatment are reported. All had required varying degrees of restraint during previous dental treatments, which had been distressing for the patient, the relatives and the ward staff. In all cases, administration of oral ketamine 10 mg/k...

journal_title：Anaesthesia

authors： Petros AJ

更新日期：1991-08-01 00:00:00

abstract：:Harold King was an analytical chemist of distinction, who worked with Sir Henry Dale and his colleagues in the Medical Research Institute, later the Medical Research Council. He helped to quash the theory that the anaesthetic action of ether was attributable to its impurities. Interest in alkaloids led to the elucidat...

journal_title：Anaesthesia

authors： Gray TC

更新日期：1991-08-01 00:00:00

abstract：:The dose requirements and side effects of morphine were compared with those of diamorphine administered by patient-controlled analgesia in 40 patients following elective total hip replacement. Patients were allocated randomly to receive in a double-blind manner either morphine or diamorphine for postoperative pain rel...

journal_title：Anaesthesia

authors： Robinson SL,Rowbotham DJ,Smith G

更新日期：1991-07-01 00:00:00

abstract：:Continuous epidural analgesia may be complicated by intravascular or subarachnoid injection of local analgesic, with disastrous consequences. One of the techniques described to prevent these complications is the aspiration test. It is the current standard of practice to employ a micropore bacterial filter for epidural...

journal_title：Anaesthesia

authors： Charlton GA,Lawes EG

更新日期：1991-07-01 00:00:00

abstract：:The influence of route of administration (extradural as compared with intravenous) of diamorphine 0.5 mg/hour as a supplement to extradural bupivacaine (0.125% at 15 ml/hour) was investigated in two groups of 20 patients who underwent major abdominal gynaecological surgery. Significantly more patients in the intraveno...

journal_title：Anaesthesia

authors： Lee A,McKeown D,Brockway M,Bannister J,Wildsmith JA

更新日期：1991-06-01 00:00:00

abstract：:The Lamtec agent monitor is a compact anaesthetic analyser designed to measure halothane, isoflurane and enflurane. It shows good linearity and stability. The faster model can be used for end-tidal measurements up to 25 breaths per minute. Calibration using a standard of the gas to be measured is recommended. ...

journal_title：Anaesthesia

authors： Humphrey SJ,Luff NP,White DC

更新日期：1991-06-01 00:00:00

abstract：:The cardiovascular effects of 20 ml 0.75% bupivacaine with adrenaline 5 micrograms/ml injected epidurally were compared with those of 20 ml 0.75% ropivacaine with adrenaline. Cardiovascular measurements were performed with a transthoracic electrical bioimpedance monitor. The maximum mean arterial blood pressure decrea...

journal_title：Anaesthesia

authors： Kerkkamp HE,Gielen MJ

更新日期：1991-05-01 00:00:00

abstract：:Cardiopulmonary resuscitation en route to hospital is performed by a single-handed operator in many British ambulances. In this study, three emergency ventilation devices, and mouth-to-mouth breathing, were compared for effectiveness in unintubated patients. Seventeen paramedics used each method on a Laerdal manikin i...

journal_title：Anaesthesia

authors： Greenslade GL

更新日期：1991-05-01 00:00:00

abstract：:A randomised, double-blind comparison of the efficacy, duration of action and side effects of two analgesic regimens following elective epidural Caesarean section is described. Patients received epidural diamorphine 3 mg or intramuscular morphine 10 mg in the immediate postoperative period. Time to next analgesia was ...

journal_title：Anaesthesia

authors： Stevens JD,Braithwaite P,Corke CF,Madej TH,Wheatley RG

更新日期：1991-04-01 00:00:00

abstract：:A laboratory study of a widely available heat and moisture exchanger marketed for paediatric use was undertaken. The deadspace, measured by volume displacement, was 12 ml, similar to that of a standard catheter mount for paediatric use. Pressure drop across the device was measured at several different flows in five sa...

journal_title：Anaesthesia

authors： Wilkinson KA,Cranston A,Hatch DJ,Fletcher ME

更新日期：1991-04-01 00:00:00

abstract：:A double-blind randomised study was performed to investigate the effect of pH adjustment of bupivacaine, with adrenaline 1:200,000, on the duration of block and pain relief after intercostal nerve blockade following thoracotomy. One group (n = 10) received bupivacaine with adrenaline 1:200,000 (pH = 4.1) and the other...

journal_title：Anaesthesia

authors： Swann DG,Armstrong PJ,Douglas E,Brockway M,Bowler GM

更新日期：1991-03-01 00:00:00

abstract：:Undetected defects in the inner tube of the Bain coaxial anaesthetic breathing system may result in a greatly increased apparatus deadspace. Several authorities have advocated tests intended to detect inner tube problems; however, the efficacy of these tests has never been validated. In this study none of the tests we...

journal_title：Anaesthesia

authors： Heath PJ,Marks LF

更新日期：1991-03-01 00:00:00

abstract：:A double-blind, randomised study was conducted to examine the efficacy of a single bolus dose of esmolol in treating surgically-induced tachycardia. Anaesthetic technique was identical in all patients, and consisted of premedication with midazolam and glycopyrronium, induction with thiopentone followed by suxamethoniu...

journal_title：Anaesthesia

authors： Whirley-Diaz J,Gold MI,Helfman SM,deLisser EA

更新日期：1991-03-01 00:00:00

abstract：:The efficacy of acupuncture and transcutaneous stimulation analgesia, supplemented by small doses of fentanyl (mean 1.2 micrograms/kg, SD 1.7) was compared with moderate-dose fentanyl anaesthesia (mean 22.9 micrograms/kg, SD 2.8) in 29 patients who underwent surgery for retroperitoneal lymph node dissection. The prese...

journal_title：Anaesthesia

authors： Kho HG,Eijk RJ,Kapteijns WM,van Egmond J

更新日期：1991-02-01 00:00:00

abstract：:Rhabdomyolysis during routine surgery was studied in three groups of patients who had surgery, with limited trauma to muscle, in the lateral and supine positions, and prone on the spinal frame. A range of blood tests was performed (before surgery, and on the first, third and seventh day after operation). These showed ...

journal_title：Anaesthesia

authors： Targa L,Droghetti L,Caggese G,Zatelli R,Roccella P

更新日期：1991-02-01 00:00:00

abstract：:The haemodynamic effects of propofol (2 mg/kg), etomidate (0.2 mg/kg) and thiopentone (4 mg/kg) were studied in 30 ASA 1 and 2 patients in whom anaesthesia had been induced with midazolam 0.1 mg/kg, fentanyl 5 micrograms/kg, vecuronium 0.1 mg/kg and atropine 10 micrograms/kg, and maintained with nitrous oxide in oxyge...

journal_title：Anaesthesia

authors： Gauss A,Heinrich H,Wilder-Smith OH

更新日期：1991-02-01 00:00:00

abstract：:A ketamine, midazolam and vecuronium infusion was used for total intravenous anesthesia in a patient with Down's syndrome, a ventricular septal defect and pulmonary hypertension. A mixture of ketamine 200 mg, midazolam 5 mg and vecuronium 12 mg in 50 ml of normal saline was infused at 0.5 ml/kg/hour. This simple techn...

journal_title：Anaesthesia

authors： Riley DP,McBride LJ

更新日期：1991-02-01 00:00:00

abstract：:A cumulative dose followed by an infusion was used to determine the dose response to suxamethonium in a patient with diagnosed myasthenia gravis who was in true remission (asymptomatic while receiving no therapy). The ED50 and ED90 values for suxamethonium were 0.08 mg/kg and 0.20 mg/kg, and an infusion rate of 3.2 mg...

journal_title：Anaesthesia

authors： Abel M,Eisenkraft JB,Patel N

更新日期：1991-01-01 00:00:00

abstract：:Factors that influence the induction of anaesthesia with propofol were investigated in a prospective study of 1000 patients. Pre-operative albumin and urea concentrations correlated with the minimum induction dose of propofol, but less strong correlations were found with haemoglobin, globulin and total protein concent...

journal_title：Anaesthesia

authors： McCleane GJ,Fogarty DF,Watters CH

更新日期：1991-01-01 00:00:00